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Merck

HTR3B

5-hydroxytryptamine (serotonin) receptor 3B, ionotropic

Synonyms:
5-HT3B
Species:
UniProtKB ID:
Gene ID:
  • Human(9177) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit B of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It is not functional as a homomeric complex, but a pentaheteromeric complex with subunit A (HTR3A) displays the full functional features of this receptor. [provided by RefSeq, Aug 2011]
  • Mouse(57014) 5-hydroxytryptamine (serotonin) receptor 3B
  • Rat(58963) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • domestic cat(101082340) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • sheep(101110267) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • cow(541055) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • naked mole-rat(101726074) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • domestic guinea pig(100736034) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
  • dog(611236) 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic

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Small Molecule - Agonist

Product Number
Description
Species
SR 57227A, solid,
Species
human
Metoclopramide hydrochloride, solid,
Species
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
(+)-Fenfluramine hydrochloride, ,
Species
human
Quipazine maleate salt, ,
Species
human

Small Molecule - Allosteric Modulator

Product Number
Description
Species
DCEBIO, ≥98% (HPLC), solid,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
Metoclopramide hydrochloride, solid,
Species
human
Tropisetron monohydrochloride, solid, ≥98% (HPLC),
Species
rat, human
Amisulpride, European Pharmacopoeia (EP) Reference Standard,
Species
human
Amisulpride, ≥98% (HPLC),
Species
human
Amisulpride, British Pharmacopoeia (BP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-HTR3B antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-HTR3B antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
Anti-HTR3B antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot

Small Molecule - Blocker

Product Number
Description
Species
Trimipramine maleate salt, ≥98% (TLC), powder,
Species
human
Zimelidine dihydrochloride, solid,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Species
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Species
human
Sertraline hydrochloride, ≥98% (HPLC),
Species
human
Fluvoxamine maleate, solid,
Species
human
Reserpine, ,
Species
human

Small Molecule - Ligand

Product Number
Description
Species
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Species
human

Small Molecule - Metabolite

Product Number
Description
Species
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Species
human

Small Molecule - Precursor

Product Number
Description
Species
5-Hydroxy-L-tryptophan, powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Htr3b,
Species
mouse