HSPB8
heat shock 22kDa protein 8
CMT2L, DHMN2, E2IG1, H11, HMN2, HMN2A, HSP22
Human HSPB8 (26353), Mouse Hspb8 (80888), Rat Hspb8 (113906), sheep HSPB8 (101108164), domestic cat HSPB8 (101093804), Zebrafish hspb8 (791580), chicken HSPB8 (416988), domestic guinea pig Hspb8 (100734199), naked mole-rat Hspb8 (101707078), dog HSPB8 (403553)
- Human(26353) Summary: The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of this gene in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, this gene appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in this gene have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease. [provided by RefSeq, Jul 2008]
- Mouse(80888) heat shock protein 8
- Rat(113906) heat shock protein B8
- sheep(101108164) heat shock 22kDa protein 8
- domestic cat(101093804) heat shock 22kDa protein 8
- Zebrafish(791580) heat shock protein, alpha-crystallin-related, b8
- chicken(416988) heat shock 22kDa protein 8
- domestic guinea pig(100734199) heat shock 22kDa protein 8
- naked mole-rat(101707078) heat shock 22kDa protein 8
- dog(403553) heat shock 22kDa protein 8
- cow(539524) heat shock 22kDa protein 8
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Antibodies
Anti-HSPB8 antibody produced in rabbit, affinity isolated antibody,
bovine, guinea pig, horse, human, mouse, rat
western blot
Anti-HSPB8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
human
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-HSPB8, (C-terminal) antibody produced in mouse, clone 5D7, purified immunoglobulin, buffered aqueous solution,
human
ELISA
western blot
western blot
Anti-HSPB8/HSP22 Antibody, clone 3K10W1, Rabbit Monoclonal, ,
human, rat
immunofluorescence
western blot
western blot
Proteins
Heat Shock Protein 22 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC),
human