HERC2
HECT and RLD domain containing E3 ubiquitin protein ligase 2
Synonyms:
D15F37S1, SHEP1, jdf2, p528
Species:
Human HERC2 (8924), Mouse Herc2 (15204), Rat Herc2 (308669), chicken HERC2 (418682), Zebrafish herc2 (558479), fruit fly HERC2 (33035), naked mole-rat Herc2 (101713485), domestic guinea pig Herc2 (100731329), cow HERC2 (535440), Horse HERC2 (100050955)
UniProtKB ID:
Gene ID:
- Human(8924) Summary: This gene belongs to the HERC gene family that encodes a group of unusually large proteins, which contain multiple structural domains. All members have at least 1 copy of an N-terminal region showing homology to the cell cycle regulator RCC1 and a C-terminal HECT (homologous to E6-AP C terminus) domain found in a number of E3 ubiquitin protein ligases. Genetic variations in this gene are associated with skin/hair/eye pigmentation variability. Multiple pseudogenes of this gene are located on chromosomes 15 and 16. [provided by RefSeq, Mar 2012]
- Mouse(15204) hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2
- Rat(308669) HECT and RLD domain containing E3 ubiquitin protein ligase 2
- chicken(418682) HECT and RLD domain containing E3 ubiquitin protein ligase 2
- Zebrafish(558479) hect domain and RLD 2
- fruit fly(33035) CG11734 gene product from transcript CG11734-RC
- naked mole-rat(101713485) HECT and RLD domain containing E3 ubiquitin protein ligase 2
- domestic guinea pig(100731329) HECT and RLD domain containing E3 ubiquitin protein ligase 2
- cow(535440) HECT and RLD domain containing E3 ubiquitin protein ligase 2
- Horse(100050955) HECT and RLD domain containing E3 ubiquitin protein ligase 2
- dog(479005) HECT and RLD domain containing E3 ubiquitin protein ligase 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-HERC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-HERC2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
immunohistochemistry