ATF4
activating transcription factor 4
Synonyms:
CREB-2, CREB2, TAXREB67, TXREB
Species:
Human ATF4 (468), Mouse Atf4 (11911), Rat Atf4 (79255), naked mole-rat Atf4 (101724287), domestic cat ATF4 (101084297), sheep ATF4 (100216465), domestic guinea pig Atf4 (100732296), cow ATF4 (509107), dog ATF4 (474503), chicken ATF4 (395693)
UniProtKB ID:
Gene ID:
- Human(468) Summary: This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2). The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication. [provided by RefSeq, Sep 2011]
- Mouse(11911) activating transcription factor 4
- Rat(79255) activating transcription factor 4
- naked mole-rat(101724287) activating transcription factor 4
- domestic cat(101084297) activating transcription factor 4 (tax-responsive enhancer element B67)
- sheep(100216465) activating transcription factor 4 (tax-responsive enhancer element B67)
- domestic guinea pig(100732296) activating transcription factor 4
- cow(509107) activating transcription factor 4 (tax-responsive enhancer element B67)
- dog(474503) activating transcription factor 4 (tax-responsive enhancer element B67)
- chicken(395693) activating transcription factor 4 (tax-responsive enhancer element B67)
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ATF4 antibody produced in mouse, clone 2E3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-phospho-ATF4 (pSer245) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry
Anti-phospho-ATF4 (pSer245) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Monoclonal Anti-ATF4 antibody produced in mouse, clone 2B3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot