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Merck

AKT3

v-akt murine thymoma viral oncogene homolog 3

Synonyms:
MPPH, PKB-GAMMA, PKBG, PRKBG, RAC-PK-gamma, RAC-gamma, STK-2
Species:
Human AKT3 (10000), Mouse Akt3 (23797), Rat Akt3 (29414), domestic guinea pig Akt3 (100724315), Zebrafish akt3 (100149794), chicken AKT3 (421497), dog AKT3 (442964), domestic cat AKT3 (101092818), cow AKT3 (100137872), Horse AKT3 (100054961) ...More
UniProtKB ID:
Q9Y243, Q0VAA6, Q5VTI1, Q5VTI2, Q96QV3, Q9UFP5
Gene ID:
  • Human(10000) Summary: The protein encoded by this gene is a member of the AKT, also called PKB, serine/threonine protein kinase family. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. This kinase has been shown to be stimulated by platelet-derived growth factor (PDGF), insulin, and insulin-like growth factor 1 (IGF1). Alternatively splice transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
  • Mouse(23797) thymoma viral proto-oncogene 3
  • Rat(29414) v-akt murine thymoma viral oncogene homolog 3
  • domestic guinea pig(100724315) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • Zebrafish(100149794) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • chicken(421497) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • dog(442964) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • domestic cat(101092818) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • cow(100137872) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • Horse(100054961) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • Domestic Rabbit(100353706) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • sheep(101118462) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)
  • naked mole-rat(101701289) v-akt murine thymoma viral oncogene homolog 3 (protein kinase B, gamma)

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Antibodies

Product Number
Description
Species Reactivity
Application
HPA026441
Anti-AKT3 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
07-383
Anti-Akt3/PKBγ Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
35-002
STK Antibody, 20X, Upstate®, from mouse,
Species Reactivity
human
Application
immunoprecipitation (IP)
05-780
Anti-Akt3/PKBγ Antibody, clone GMA104, clone GMA104, Upstate®, from mouse,
Species Reactivity
human
Application
immunoprecipitation (IP)
western blot
SAB4300259
Anti-phospho-AKT1/AKT2/AKT3 (pTyr315/pTyr316/pTyr312) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
SML0428
GSK690693, ≥98% (HPLC),
Species
human

Proteins

Product Number
Description
Species
14-502-M
Akt3/PKBγ (S472D) Protein, active, 10 µg, Active, N-terminal His6-tagged, recombinant human Akt3/PKBγ, amino acids 117-end, containing a S472D mutation. For use in Kinase Assays.,
Species
human
A0983
AKT3, active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human
MSST0054
SILu™Lite AKT3, RAC-gamma serine/threonine-protein kinase human, recombinant, expressed in HEK 293 cells, MS Protein Standard,
Species
human
MSST0053
SILu™Prot AKT3, RAC-gamma serine/threonine-protein kinase human, recombinant, expressed in HEK 293 cells, SIL MS Protein Standard, 13C and 15N-labeled,
Species
human

esiRNA

Product Number
Description
Species
EHU067201
MISSION® esiRNA, targeting human AKT3,
Species
human
EMU055721
MISSION® esiRNA, targeting mouse Akt3,
Species
mouse

Small Molecule - Substrate

Product Number
Description
Species
12-549
STK Substrate 2, STK Substrate 2 primarily used in Kinase Assays.,
Species
human