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ABCA1

ATP-binding cassette, sub-family A (ABC1), member 1

Synonyms:
ABC-1, ABC1, CERP, HDLDT1, TGD
Species:
UniProtKB ID:
Gene ID:
  • Human(19) Summary: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq, Jul 2008]
  • Mouse(11303) ATP-binding cassette, sub-family A (ABC1), member 1
  • Rat(313210) ATP-binding cassette, subfamily A (ABC1), member 1
  • chicken(373945) ATP-binding cassette, sub-family A (ABC1), member 1
  • cow(535379) ATP-binding cassette, sub-family A (ABC1), member 1
  • sheep(101119015) ATP-binding cassette, sub-family A (ABC1), member 1
  • domestic cat(101083885) ATP-binding cassette, sub-family A (ABC1), member 1
  • Horse(100054241) ATP-binding cassette, sub-family A (ABC1), member 1
  • dog(481651) ATP-binding cassette, sub-family A (ABC1), member 1
  • Thale Cress(818768) ABC transporter A family member 1
  • naked mole-rat(101704546) ATP-binding cassette, sub-family A (ABC1), member 1
  • domestic guinea pig(100720792) ATP-binding cassette, sub-family A (ABC1), member 1
  • Domestic Rabbit(100356765) ATP-binding cassette, sub-family A (ABC1), member 1

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Small Molecule - Agonist

Product Number
Description
Species
T0901317, ≥98%,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-ABCA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-ABCA1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-ABCA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-ABCA1 Antibody, clone AB.H10, clone AB.H10, Chemicon®, from mouse,
Species Reactivity
chicken, human, mouse
Application
ELISA
immunohistochemistry

immunoprecipitation (IP)

western blot
Anti-ABCA1 Antibody, clone MABI98-7, clone MAB198-7, from rat,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot

Small Molecule - Inhibitor

Product Number
Description
Species
Probucol, United States Pharmacopeia (USP) Reference Standard,
Species
human
Probucol, analytical standard,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Abca1,
Species
mouse