Skip to Content
Merck

1.12120

SAFC

Calcium carbonate

precipitated (≤ 0.0001% Al), EMPROVE® ESSENTIAL, Ph. Eur., BP, JP, USP, FCC, E 170

Pharma Manufacturing

Sign Into View Organizational & Contract Pricing


About This Item

Linear Formula:
CaCO3
CAS Number:
Molecular Weight:
100.09
Beilstein:
8008338
MDL number:
UNSPSC Code:
12352302
E Number:
E170
EC Index Number:
207-439-9

Pricing and availability is not currently available.

Agency

BP
JP
Ph. Eur.
USP

Quality Level

reg. compliance

FCC

product line

EMPROVE® ESSENTIAL

form

solid

potency

6450 mg/kg LD50, oral (Rat)
>2000 mg/kg LD50, skin (Rat)

pH

9.5-10.5 (20 °C, 100 g/L in H2O, slurry)

mp

825 °C (decomposition)

density

2.93 g/mL at 25 °C (lit.)

application(s)

liquid formulation
pharmaceutical
solid formulation

Looking for similar products? Visit Product Comparison Guide

General description

Finding the right excipient that matches your needs as well as regulatory demands can be a complicated challenge in formulation. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Calcium carbonate is typically used as alkalizer or mineral supplement in solid formulations. The low aluminum content is relevant for baby food application.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

13 - Non Combustible Solids

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


  • What is the Emprove® Program?

    The Emprove® Program is a system providing comprehensive and thorough documentation of our filters and single-use components, pharma raw materials, and starting materials. Four document types are included with an Emprove® Program subscription:

    Material Qualification Dossier

    Free of charge - Sign in to download

    Quality Management Dossier (Open Access)

    Free of charge - Sign in to download

    Quality Management Dossier (Open Access)

    Free of charge - Sign in to download

    Operational Excellence Dossier

    Available by subscription or for a fee

    Learn more about the benefits an Emprove® Program subscription can provide
    Why are these documents unavailable?
    Emprove® Dossiers contain information intended to support the registration process and risk assessment activities of pharmaceutical producers and contain confidential information. Please contact us if you would like access.

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    J P Hilton-Proctor et al.
    European journal of medicinal chemistry, 191, 112120-112120 (2020-03-03)
    N-Methylpyrrolidone is one of several chemotypes that have been described as a mimetic of acetyl-lysine in the development of bromodomain inhibitors. In this paper, we describe the synthesis of a 4-phenyl substituted analogue - 1-methyl-4-phenylpyrrolidin-2-one - and the use of

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service