Skip to Content
Merck
  • TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis.

TAK1 inhibition attenuates both inflammation and fibrosis in experimental pneumoconiosis.

Cell discovery (2017-07-13)
Jie Li, Chao Liang, Zong-Kang Zhang, Xiaohua Pan, Songlin Peng, Wing-Sze Lee, Aiping Lu, Zhixiu Lin, Ge Zhang, Wing-Nang Leung, Bao-Ting Zhang
PMID28698801
ABSTRACT

Pneumoconiosis, caused by inhalation of mineral dusts, is a major occupational disease worldwide. Currently, there are no effective drugs owing to a lack of potential therapeutic targets during either the inflammation or fibrosis molecular events in pneumoconiosis. Here, we performed microarrays to identify aberrantly expressed genes in the above molecular events