sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

sp3-sp3 Coupling reactions in the synthesis of natural products and biologically active molecules.

Natural product reports (2014-02-28)

Egor Geist, Andreas Kirschning, Thomas Schmidt

ABSTRACT

This Highlight covers the current status of relatively unexplored sp(3)-sp(3) cross-coupling reactions with particular focus on natural product and related syntheses.

MATERIALS

Product Number

Brand

Product Description

203904

Sigma-Aldrich

Nickel, powder, <150 μm, 99.99% trace metals basis

510068

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 3202, slurry, in H₂O, active catalyst

510033

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2400, slurry, in H₂O, active catalyst

267058

Sigma-Aldrich

Nickel, wire, diam. 0.5 mm, ≥99.99% trace metals basis

268283

Sigma-Aldrich

Nickel, powder, <1 μm, 99.8% trace metals basis

357634

Sigma-Aldrich

Nickel, wire, diam. 0.25 mm, ≥99.9%

510041

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 4200, slurry, in H₂O, active catalyst

268259

Sigma-Aldrich

Nickel, foil, thickness 0.125 mm, ≥99.9%

221678

Sigma-Aldrich

Raney^®-Nickel, W.R. Grace and Co. Raney^® 2800, slurry, in H₂O, active catalyst

267007

Sigma-Aldrich

Nickel, foil, thickness 0.25 mm, 99.995% trace metals basis

767484

Sigma-Aldrich

Nickel, sputtering target, diam. × thickness 2.00 in. × 0.25 in., 99.95% trace metals basis

GF40064756

Nickel, foil, 2m coil, thickness 0.01mm, 99.95%

GF04391591

Nickel, mesh, 100x250mm, nominal aperture 0.73mm, wire diameter 0.25mm, 26x26 wires/inch, open area 55%, plain weave mesh, 99%

GF32263354

Nickel, foil, 25x25mm, thickness 0.25mm, as rolled, 99.99+%

GF35122092

Nickel, mesh, 65x65mm, nominal aperture 0.04mm, thickness 0.004mm, wire diameter 0.011mm, 500 wires/inch, open area 60%, electro-formed mesh, 99.9%

GF50887255

Nickel, wire reel, 10m, diameter 1.0mm, hard, 99.98%

GF97678995

Nickel, wire reel, 10m, diameter 0.25mm, as drawn, 99.99+%

GF17897596

Nickel, pellets, 100g, max. size 5mm, 99.99+%

GF50050213

Nickel, wire reel, 10m, diameter 0.75mm, as drawn, 99%

GF66892922

Nickel, wire reel, 100m, diameter 0.5mm, hard, 99.98%

GF39205931

Nickel, rod, 100mm, diameter 25.4mm, 99.98%

GF69167920

Nickel, rod, 100mm, diameter 3.0mm, 99%

GF58660746

Nickel, rod, 200mm, diameter 2.0mm, 99.99+%

GF51944665

Nickel, rod, 200mm, diameter 3.0mm, 99%

GF90754241

Nickel, rod, 100mm, diameter 40mm, 99%

GF20561385

Nickel, rod, 100mm, diameter 5.0mm, 99.99+%

GF83584143

Nickel, rod, 100mm, diameter 2.0mm, 99.99+%

GF45193697

Nickel, rod, 100mm, diameter 2.0mm, annealed, 99%

GF18587975

Nickel, sphere, 100pcs, diameter 1.0mm, precision sphere grade 200, 99%

GF38653869

Nickel, foil, light tested, 25x25mm, thickness 0.0125mm, 99.9%