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[Sclerodermiform porphyria cutanea tarda. Ultrastructural study].

Medicina cutanea ibero-latino-americana (1985-01-01)
J Ocaña, I Pérez de Vargas, M L Wilhelmi, V Crespo, R Pastor, F S Fajardo, M L Delgado
ABSTRACT

Approximately 30% of patients affected of PCT present scleroderma-like lesion of the skin. Two cases of PCT, presenting scleroderma-like lesions are reported. The patients were diabetic but not alcoholic and tolerate relatively well sunshine. Porphyrin elimination diminished with urine alkalinization and phlebotomies, and the scleroderma-like lesions improved with N-acetyl-hydroxy-proline administration.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
trans-1-Acetyl-4-hydroxy-L-proline, ≥98%