Convergent total syntheses of fluvibactin and vibriobactin using molybdenum(VI) oxide-catalyzed dehydrative cyclization as a key step.

Convergent total syntheses of fluvibactin and vibriobactin using molybdenum(VI) oxide-catalyzed dehydrative cyclization as a key step.

Chemical communications (Cambridge, England) (2008-07-26)

Akira Sakakura, Shuhei Umemura, Kazuaki Ishihara

ABSTRACT

Efficient total syntheses of fluvibactin and vibriobactin have been achieved via molybdenum(VI) oxide-catalyzed dehydrative cyclization, Sb(OEt)(3)-catalyzed ester-amide transformation, and WSCI and HOAt-promoted dehydrative amide formation.

MATERIALS

Product Number

Brand

Product Description

V800389

Sigma-Aldrich

Sodium molybdate, LR, ≥99.5%

M1003

Sigma-Aldrich

Sodium molybdate dihydrate, ≥99.5%

737860

Sigma-Aldrich

Sodium molybdate, anhydrous, powder, −100 mesh particle size, 99.9% trace metals basis

M1651

Sigma-Aldrich

Sodium molybdate dihydrate, ≥99.5%, suitable for plant cell culture

331058

Sigma-Aldrich

Sodium molybdate dihydrate, ACS reagent, ≥99%

480967

Sigma-Aldrich

Sodium molybdate dihydrate, 99.99% trace metals basis

243655

Sigma-Aldrich

Sodium molybdate, ≥98%