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Highly enantioselective synthesis of isoxazoline N-oxides.

Chemical communications (Cambridge, England) (2008-05-16)
Chun-Yin Zhu, Xian-Ming Deng, Xiu-Li Sun, Jun-Cheng Zheng, Yong Tang
PMID18478708
ABSTRACT

The reaction of cinchonidine (cinchonine)-derived ammonium salts with nitroolefins in the presence of Cs2CO3 to afford optically active isoxazoline N-oxides with excellent ee and high de values has been developed.

MATERIALS
Product Number
Brand
Product Description
C80407
Sigma-Aldrich
Cinchonidine, 96%