- Chromosome stability, DNA recombination and the BRCA2 tumour suppressor.
Chromosome stability, DNA recombination and the BRCA2 tumour suppressor.
Current opinion in cell biology (2001-05-10)
A R Venkitaraman
PMID11343905
ABSTRACT
The BRCA2 tumour suppressor works in DNA recombination and repair pathways to preserve genome integrity. Recent progress provides fresh insights into its role as a regulator of the Rad51 recombination protein, underpinning a model in which BRCA2's involvement in chromosome stability and tumour suppression arises from its participation in recombinational processes essential for DNA replication.
MATERIALS
Product Number
Brand
Product Description