S8647

Sulfacetamide sodium salt monohydrate

• Empirical Formula (Hill Notation): C₈H₉N₂NaO₃S · H₂O
• CAS Number: 6209-17-2
• Molecular Weight: 254.24
• MDL number: MFCD00149555
• UNSPSC Code: 51102829
• PubChem Substance ID: 24899806
• NACRES: NA.85

Properties

• form: powder
• color: white to off-white
• solubility: H₂O: soluble 50 mg/mL
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria; mycoplasma
• Mode of action: DNA synthesis | interferes; enzyme | inhibits
• SMILES string: NC1=CC=C(S(N([Na])C(C)=O)(=O)=O)C=C1.O
• InChI: 1S/C8H10N2O3S.Na.H2O/c1-6(11)10-14(12,13)8-4-2-7(9)3-5-8;;/h2-5H,9H2,1H3,(H,10,11);;1H2/q;+1;/p-1
• InChI key: IHCDKJZZFOUARO-UHFFFAOYSA-M

Description

General description

Chemical structure: sulfonamide

Biochem/physiol Actions

Sulfacetamide is a sulfonamide antibiotic that blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. Sulfacetamide is a competitive inhibitor of bacterial para-aminobenzoic acid (PABA), which is required for bacterial synthesis of folic acid. It is active against Gram positive bacteria, Gram negative bacteria and Chlamydia. Mode of resistance is via the alteration of dihydropteroate synthase or alternative pathway for folic acid synthesis.

Packaging

100G

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Storage class (TRGS 510): Non Combustible Solids

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves