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A5806

Sigma-Aldrich

9-Amino-6-chloro-2-methoxyacridine

suitable for fluorescence, ≥95%

Synonym(s):

ACMA

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About This Item

Empirical Formula (Hill Notation):
C14H11ClN2O
CAS Number:
3548-09-2
Molecular Weight:
258.70
MDL number:
MFCD07374304
UNSPSC Code:
12352200
PubChem Substance ID:
24891024

Assay

≥95%

suitability

suitable for fluorescence

storage temp.

−20°C

SMILES string

COc1ccc2nc3cc(Cl)ccc3c(N)c2c1

InChI

1S/C14H11ClN2O/c1-18-9-3-5-12-11(7-9)14(16)10-4-2-8(15)6-13(10)17-12/h2-7H,1H3,(H2,16,17)

InChI key

IHHSSHCBRVYGJX-UHFFFAOYSA-N

Pictograms

Health hazardExclamation mark
GHS08,GHS07

Signal Word

Warning

Hazard Statements

H315,H319,H335,H351

Hazard Classifications

Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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L Helfenbaum et al.
Journal of bioenergetics and biomembranes, 29(1), 71-80 (1997-02-01)
As part of the ongoing studies aimed at elucidating the mechanism of the energy conserving function of mitochondrial complex I, NADH: ubiquinone (Q) reductase, we have investigated how short-chain Q analogs activate the proton pumping function of this complex. Using
Yun Shi et al.
Bioconjugate chemistry, 16(2), 306-311 (2005-03-17)
Chirally pure phosphoramidite monomers bearing 9-amino-6-chloro-2-methoxyacridine were synthesized from D- or L-threoninol and omega-aminocarboxylic acid, and incorporated into oligonucleotides. These acridine-DNA conjugates formed stable duplexes with complementary RNA because of intercalation of the acridine to DNA/RNA heteroduplexes. The stability of
Sakurako Ono et al.
The Journal of biological chemistry, 279(32), 33409-33412 (2004-06-04)
In a rotary motor F1F0-ATP synthase, F0 works as a proton motor; the oligomer ring of F0c-subunits (c-ring) rotates relative to the F0ab2 domain as protons pass through F0 down the gradient. F0ab2 must exert dual functions during rotation, that
S Hess et al.
Journal of the American Chemical Society, 123(41), 10046-10055 (2001-10-11)
From previous thermal and photoinduced charge-transfer reactions in duplex DNA there is accumulative evidence for an attenuation parameter beta of the distance dependence in the range 0.6-0.8 A(-1), with the exception of one specific system exhibiting beta = 1.5 A(-1)
Ryuichi Ohgaki et al.
Biochimica et biophysica acta, 1712(2), 185-196 (2005-06-14)
The Saccharomyces cerevisiae Nha1p, a plasma membrane protein belonging to the monovalent cation/proton antiporter family, plays a key role in the salt tolerance and pH regulation of cells. We examined the molecular function of Nha1p by using secretory vesicles isolated
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