Skip to Content
Merck

TYW1B

tRNA-yW synthesizing protein 1 homolog B (S. cerevisiae)

Synonyms:
LINC00069, NCRNA00069, RSAFD2
Species:
Human TYW1B (441250)
UniProtKB ID:
Q6NUM6, A6NG09, Q3KQX2
Gene ID:
  • Human(441250) Summary: Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine (yW). The human genome contains two closely related genes that putatively function in wybutosine synthesis. The open reading frame of this locus is disrupted in some individuals. Thus, this locus appears to be an evolving pseudogene, but may still be functional in some members of the population. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.