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Merck

TLR1

toll-like receptor 1

Synonyms:
CD281, TIL, TIL. LPRS5, rsc786
Species:
Human TLR1 (7096), Mouse Tlr1 (21897), Rat Tlr1 (305354), domestic guinea pig Tlr1 (100732850), Goat TLR1 (100861260), Zebrafish tlr1 (403127), Horse TLR1 (100049577), domestic cat TLR1 (493660), sheep TLR1 (554261), cow TLR1 (574090) ...More
UniProtKB ID:
Q15399, D1CS39, D1CS41, O15452, Q32MK3, Q9UG90
Gene ID:
  • Human(7096) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is ubiquitously expressed, and at higher levels than other TLR genes. Different length transcripts presumably resulting from use of alternative polyadenylation site, and/or from alternative splicing, have been noted for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(21897) toll-like receptor 1
  • Rat(305354) toll-like receptor 1
  • domestic guinea pig(100732850) toll-like receptor 1
  • Goat(100861260) toll-like receptor 1
  • Zebrafish(403127) toll-like receptor 1
  • Horse(100049577) toll-like receptor 1
  • domestic cat(493660) toll-like receptor 1
  • sheep(554261) toll-like receptor 1
  • cow(574090) toll-like receptor 1
  • naked mole-rat(101717639) toll-like receptor 1
  • dog(488834) toll-like receptor 1

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ELISA

Product Number
Description
Species
RAB1748
Human TLR1 ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
PRS3639
Anti-TLR1 (ab1) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human, mouse
Application
ELISA
immunofluorescence
immunohistochemistry
western blot