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Merck

SRSF1

serine/arginine-rich splicing factor 1

Synonyms:
ASF, SF2, SF2p33, SFRS1, SRp30a
Species:
Human SRSF1 (6426), Mouse Srsf1 (110809), Rat Srsf1 (689890), dog SRSF1 (609693), chicken SRSF1 (772264), sheep SRSF1 (101121021), domestic guinea pig Srsf1 (100721786), Horse SRSF1 (100056763), naked mole-rat Srsf1 (101699866), cow SRSF1 (615796)
UniProtKB ID:
Q07955, B2R6Z7, D3DTZ3, Q13809
Gene ID:
  • Human(6426) Summary: This gene encodes a member of the arginine/serine-rich splicing factor protein family, and functions in both constitutive and alternative pre-mRNA splicing. The protein binds to pre-mRNA transcripts and components of the spliceosome, and can either activate or repress splicing depending on the location of the pre-mRNA binding site. The protein's ability to activate splicing is regulated by phosphorylation and interactions with other splicing factor associated proteins. Multiple transcript variants encoding different isoforms have been found for this gene. In addition, a pseudogene of this gene has been found on chromosome 13. [provided by RefSeq, Sep 2010]
  • Mouse(110809) serine/arginine-rich splicing factor 1
  • Rat(689890) serine/arginine-rich splicing factor 1
  • dog(609693) serine/arginine-rich splicing factor 1
  • chicken(772264) serine/arginine-rich splicing factor 1
  • sheep(101121021) serine/arginine-rich splicing factor 1
  • domestic guinea pig(100721786) serine/arginine-rich splicing factor 1
  • Horse(100056763) serine/arginine-rich splicing factor 1
  • naked mole-rat(101699866) serine/arginine-rich splicing factor 1
  • cow(615796) serine/arginine-rich splicing factor 1
  • domestic cat(101100012) serine/arginine-rich splicing factor 1

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Antibodies

Product Number
Description
Species Reactivity
Application
SAB5701502
Anti-SRSF1/SF2/ASF antibody produced in rabbit, ,
Species Reactivity
human
Application
immunohistochemistry
western blot

Proteins

Product Number
Description
Species
SRP2104
Arginine Splicing Factor, His tagged human, recombinant, expressed in insect cells, ≥85% (SDS-PAGE),
Species
human