Skip to Content
Merck

SF3B4

splicing factor 3b, subunit 4, 49kDa

Synonyms:
AFD1, Hsh49, SAP49, SF3b49
Species:
Human SF3B4 (10262), Mouse Sf3b4 (107701), Rat Sf3b4 (295270), sheep SF3B4 (101101849), chicken SF3B4 (426042), cow SF3B4 (506123), Zebrafish sf3b4 (192318), domestic guinea pig Sf3b4 (100719464), domestic cat SF3B4 (101081822), naked mole-rat Sf3b4 (101712760)
UniProtKB ID:
Q15427, Q5SZ63
Gene ID:
  • Human(10262) Summary: This gene encodes one of four subunits of the splicing factor 3B. The protein encoded by this gene cross-links to a region in the pre-mRNA immediately upstream of the branchpoint sequence in pre-mRNA in the prespliceosomal complex A. It also may be involved in the assembly of the B, C and E spliceosomal complexes. In addition to RNA-binding activity, this protein interacts directly and highly specifically with subunit 2 of the splicing factor 3B. This protein contains two N-terminal RNA-recognition motifs (RRMs), consistent with the observation that it binds directly to pre-mRNA. [provided by RefSeq, Jul 2008]
  • Mouse(107701) splicing factor 3b, subunit 4
  • Rat(295270) splicing factor 3b, subunit 4
  • sheep(101101849) splicing factor 3b, subunit 4, 49kDa
  • chicken(426042) splicing factor 3b, subunit 4, 49kDa
  • cow(506123) splicing factor 3b, subunit 4, 49kDa
  • Zebrafish(192318) splicing factor 3b, subunit 4
  • domestic guinea pig(100719464) splicing factor 3b, subunit 4, 49kDa
  • domestic cat(101081822) splicing factor 3b, subunit 4, 49kDa
  • naked mole-rat(101712760) splicing factor 3b, subunit 4, 49kDa
  • dog(483177) splicing factor 3b, subunit 4, 49kDa

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.