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Merck

SCO2

SCO2 cytochrome c oxidase assembly protein

Synonyms:
CEMCOX1, MYP6, SCO1L
Species:
Human SCO2 (9997), Mouse Sco2 (100126824), Thale Cress SCO2 (821456), chicken SCO2 (429671), Zebrafish sco2 (606683), dog SCO2 (481187), cow SCO2 (100125923)
UniProtKB ID:
O43819, Q3T1B5, Q9UK87
Gene ID:
  • Human(9997) Summary: Cytochrome c oxidase (COX) catalyzes the transfer of electrons from cytochrome c to molecular oxygen, which helps to maintain the proton gradient across the inner mitochondrial membrane that is necessary for aerobic ATP production. Human COX is a multimeric protein complex that requires several assembly factors; this gene encodes one of the COX asembly factors. The encoded protein is a metallochaperone that is involved in the biogenesis of cytochrome c oxidase subunit II. Mutations in this gene are associated with fatal infantile encephalocardiomyopathy. [provided by RefSeq, Dec 2009]
  • Mouse(100126824) SCO cytochrome oxidase deficient homolog 2 (yeast)
  • Thale Cress(821456) disulfide-isomerase SCO2
  • chicken(429671) SCO cytochrome oxidase deficient homolog 2 (yeast)
  • Zebrafish(606683) SCO cytochrome oxidase deficient homolog 2 (yeast)
  • dog(481187) SCO cytochrome oxidase deficient homolog 2 (yeast)
  • cow(100125923) SCO cytochrome oxidase deficient homolog 2 (yeast)

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