SAT1
spermidine/spermine N1-acetyltransferase 1
Synonyms:
DC21, KFSD, KFSDX, SAT, SSAT, SSAT-1
Species:
Human SAT1 (6303), Mouse Sat1 (20229), Rat Sat1 (302642), sheep SAT1 (101113463), cow SAT1 (508861), dog SAT1 (480865), domestic cat SAT1 (101093752), domestic guinea pig Sat1 (100715782), chicken SAT1 (374006), naked mole-rat Sat1 (101726536)
UniProtKB ID:
Gene ID:
- Human(6303) Summary: The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]
- Mouse(20229) spermidine/spermine N1-acetyl transferase 1
- Rat(302642) spermidine/spermine N1-acetyl transferase 1
- sheep(101113463) spermidine/spermine N1-acetyltransferase 1
- cow(508861) spermidine/spermine N1-acetyltransferase 1
- dog(480865) spermidine/spermine N1-acetyltransferase 1
- domestic cat(101093752) spermidine/spermine N1-acetyltransferase 1
- domestic guinea pig(100715782) spermidine/spermine N1-acetyltransferase 1
- chicken(374006) spermidine/spermine N1-acetyltransferase 1
- naked mole-rat(101726536) spermidine/spermine N1-acetyltransferase 1
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