PSPC1
paraspeckle component 1
Synonyms:
PSP1
Species:
Human PSPC1 (55269), Mouse Pspc1 (66645), Rat Pspc1 (305910), Zebrafish pspc1 (692285), chicken PSPC1 (418955), cow PSPC1 (506696), naked mole-rat Pspc1 (101714198), domestic guinea pig Pspc1 (100713500), sheep PSPC1 (101119830), domestic cat PSPC1 (101081777)
UniProtKB ID:
Gene ID:
- Human(55269) Summary: This gene encodes a nucleolar protein that localizes to punctate subnuclear structures that occur close to splicing speckles, known as paraspeckles. These paraspeckles are composed of RNA-protein structures that include a non-coding RNA, NEAT1/Men epsilon/beta, and the Drosophila Behavior Human Splicing family of proteins, which include the product of this gene and the P54NRB/NONO and PSF/SFPQ proteins. Paraspeckles may function in the control of gene expression via an RNA nuclear retention mechanism. The protein encoded by this gene is found in paraspeckles in transcriptionally active cells, but it localizes to unique cap structures at the nucleolar periphery when RNA polymerase II transcription is inhibited, or during telophase. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene, which is also located on chromosome 13, has been identified. [provided by RefSeq, Aug 2011]
- Mouse(66645) paraspeckle protein 1
- Rat(305910) paraspeckle component 1
- Zebrafish(692285) paraspeckle component 1
- chicken(418955) paraspeckle component 1
- cow(506696) paraspeckle component 1
- naked mole-rat(101714198) paraspeckle component 1
- domestic guinea pig(100713500) paraspeckle component 1
- sheep(101119830) paraspeckle component 1
- domestic cat(101081777) paraspeckle component 1
- dog(477347) paraspeckle component 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PSPC1 (N-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot
western blot
Anti-PSPC1 (C-terminal) antibody produced in rabbit, ~1.0 mg/mL, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-PSPC1 antibody, Mouse monoclonal, clone 1L4, purified from hybridoma cell culture,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot
western blot