PRKCB
protein kinase C, beta
Synonyms:
PKC-beta, PKCB, PRKCB1, PRKCB2
Species:
Human PRKCB (5579), Mouse Prkcb (18751), Rat Prkcb (25023), Domestic Rabbit PRKCB (100037719), sheep PRKCB (101118410), naked mole-rat Prkcb (101722702), domestic cat PRKCB (101088970), chicken PRKCB (416567), dog PRKCB (489968), cow PRKCB (282325)
UniProtKB ID:
Gene ID:
- Human(5579) Summary: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
- Mouse(18751) protein kinase C, beta
- Rat(25023) protein kinase C, beta
- Domestic Rabbit(100037719) protein kinase C, beta
- sheep(101118410) protein kinase C, beta
- naked mole-rat(101722702) protein kinase C, beta
- domestic cat(101088970) protein kinase C, beta
- chicken(416567) protein kinase C, beta
- dog(489968) protein kinase C, beta
- cow(282325) protein kinase C, beta
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Small Molecule - Agonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Phospho-PKCalpha/beta II-T638/641 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
ANTI-PKC BETA2(C-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human, mouse, primate, rat
Application
immunohistochemistry
western blot
western blot
Monoclonal Anti-Protein Kinase C (PKC) antibody produced in mouse, clone MC5, ascites fluid,
Species Reactivity
bovine, human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)
microarray
western blot
immunoprecipitation (IP)
microarray
western blot
Anti-phospho-PKC-pan (pThr497) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
Protein kinase CβII isozyme human, >85% (SDS-PAGE), recombinant, expressed in baculovirus infected insect cells, buffered aqueous glycerol solution,
Species
human