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Merck

PLA2G6

phospholipase A2, group VI (cytosolic, calcium-independent)

Synonyms:
CaI-PLA2, GVI, INAD1, IPLA2-VIA, NBIA2, NBIA2A, NBIA2B, PARK14, PLA2, PNPLA9, iPLA2, iPLA2beta
Species:
UniProtKB ID:
Gene ID:
  • Human(8398) Summary: The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date. [provided by RefSeq, Dec 2010]
  • Mouse(53357) phospholipase A2, group VI
  • Rat(360426) phospholipase A2, group VI (cytosolic, calcium-independent)
  • Domestic Rabbit(100008961) phospholipase A2, group VI (cytosolic, calcium-independent)
  • cow(535381) phospholipase A2, group VI (cytosolic, calcium-independent)
  • naked mole-rat(101710669) phospholipase A2, group VI (cytosolic, calcium-independent)
  • sheep(101103799) phospholipase A2, group VI (cytosolic, calcium-independent)
  • chicken(418028) phospholipase A2, group VI (cytosolic, calcium-independent)
  • domestic guinea pig(100726758) phospholipase A2, group VI (cytosolic, calcium-independent)
  • Zebrafish(406370) phospholipase A2, group VI (cytosolic, calcium-independent)
  • Horse(100055064) phospholipase A2, group VI (cytosolic, calcium-independent)
  • dog(481256) phospholipase A2, group VI (cytosolic, calcium-independent)
  • domestic cat(101095350) phospholipase A2, group VI (cytosolic, calcium-independent)

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Phospholipase A2 (iPLA2) (C-terminal region) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-PLA2G6 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human, mouse
Application
western blot
Anti-Phospholipase A2 (iPLA2) antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PLA2G6,
Species
human