PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
Synonyms:
MOM1, PLA2, PLA2B, PLA2L, PLA2S, PLAS1, sPLA2
Species:
Human PLA2G2A (5320), Mouse Pla2g2a (18780), Rat Pla2g2a (29692), domestic guinea pig Pla2g2a (100135599), cow PLA2G2A (521383), cow PLA2G2A (507201), chicken PLA2G2A (426748)
UniProtKB ID:
Gene ID:
- Human(5320) Summary: The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]
- Mouse(18780) phospholipase A2, group IIA (platelets, synovial fluid)
- Rat(29692) phospholipase A2, group IIA (platelets, synovial fluid)
- domestic guinea pig(100135599) phospholipase A2, group IIA (platelets, synovial fluid)
- cow(521383) phospholipase A2, group IIA (platelets, synovial fluid)
- cow(507201) phospholipase A2, group IIA (platelets, synovial fluid)
- chicken(426748) phospholipase A2, group IIA (platelets, synovial fluid)
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