PJA1
praja ring finger 1, E3 ubiquitin protein ligase
Synonyms:
PRAJA1, RNF70
Species:
Human PJA1 (64219), Mouse Pja1 (18744), sheep PJA1 (101120806), naked mole-rat Pja1 (101704357), domestic cat PJA1 (101083066), Horse PJA1 (100065473), cow PJA1 (786612), dog PJA1 (480949)
UniProtKB ID:
Gene ID:
- Human(64219) Summary: This gene encodes an enzyme that has E2-dependent E3 ubiquitin-protein ligase activity. This enzyme belongs to a class of ubiquitin ligases that include a RING finger motif, and it can interact with the E2 ubiquitin-conjugating enzyme UbcH5B. This gene is located in an area of chromosome X where several X-linked mental retardation disorders have been associated, and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome, though a direct link to any disorder has yet to be demonstrated. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2010]
- Mouse(18744) praja1, RING-H2 motif containing
- sheep(101120806) praja ring finger 1, E3 ubiquitin protein ligase
- naked mole-rat(101704357) praja ring finger 1, E3 ubiquitin protein ligase
- domestic cat(101083066) praja ring finger 1, E3 ubiquitin protein ligase
- Horse(100065473) praja ring finger 1, E3 ubiquitin protein ligase
- cow(786612) praja ring finger 1
- dog(480949) praja ring finger 1, E3 ubiquitin protein ligase
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