PHOX2A
paired-like homeobox 2a
Synonyms:
ARIX, CFEOM2, FEOM2, NCAM2, PMX2A
Species:
Human PHOX2A (401), Mouse Phox2a (11859), Rat Phox2a (116648), naked mole-rat Phox2a (101698435), Zebrafish phox2a (404602), chicken PHOX2A (395595), dog PHOX2A (485208), domestic cat PHOX2A (101095370), sheep PHOX2A (101103348), cow PHOX2A (507670)
UniProtKB ID:
Gene ID:
- Human(401) Summary: The protein encoded by this gene contains a paired-like homeodomain most similar to that of the Drosophila aristaless gene product. The encoded protein plays a central role in development of the autonomic nervous system. It regulates the expression of tyrosine hydroxylase and dopamine beta-hydroxylase, two catecholaminergic biosynthetic enzymes essential for the differentiation and maintenance of the noradrenergic neurotransmitter phenotype. The encoded protein has also been shown to regulate transcription of the alpha3 nicotinic acetylcholine receptor gene. Mutations in this gene have been associated with autosomal recessive congenital fibrosis of the extraocular muscles. [provided by RefSeq, Jul 2008]
- Mouse(11859) paired-like homeobox 2a
- Rat(116648) paired-like homeobox 2a
- naked mole-rat(101698435) paired-like homeobox 2a
- Zebrafish(404602) paired-like homeobox 2a
- chicken(395595) paired-like homeobox 2a
- dog(485208) paired-like homeobox 2a
- domestic cat(101095370) paired-like homeobox 2a
- sheep(101103348) paired-like homeobox 2a
- cow(507670) paired-like homeobox 2a
- domestic guinea pig(100732349) paired-like homeobox 2a
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-PHOX2A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence