PADI3
peptidyl arginine deiminase, type III
Synonyms:
PAD3, PDI3
Species:
Human PADI3 (51702), Mouse Padi3 (18601), Rat Padi3 (29520), naked mole-rat Padi3 (101722435), chicken PADI3 (395910), dog PADI3 (478216), Horse PADI3 (100049897), domestic cat PADI3 (101085813), cow PADI3 (508160), sheep PADI3 (443369) ...More
UniProtKB ID:
Gene ID:
- Human(51702) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type III enzyme modulates hair structural proteins, such as filaggrin in the hair follicle and trichohyalin in the inner root sheath, during hair follicle formation. Together with the type I enzyme, this enzyme may also play a role in terminal differentiation of the epidermis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
- Mouse(18601) peptidyl arginine deiminase, type III
- Rat(29520) peptidyl arginine deiminase, type III
- naked mole-rat(101722435) peptidyl arginine deiminase, type III
- chicken(395910) peptidyl arginine deiminase, type III
- dog(478216) peptidyl arginine deiminase, type III
- Horse(100049897) peptidyl arginine deiminase, type III
- domestic cat(101085813) peptidyl arginine deiminase, type III
- cow(508160) peptidyl arginine deiminase, type III
- sheep(443369) peptidyl arginine deiminase, type III
- Domestic Rabbit(100350962) peptidyl arginine deiminase, type III
- domestic guinea pig(100727956) peptidyl arginine deiminase, type III
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