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Merck

P2RX3

purinergic receptor P2X, ligand-gated ion channel, 3

Synonyms:
P2X3
Species:
Human P2RX3 (5024), Mouse P2rx3 (228139), Rat P2rx3 (81739), domestic guinea pig P2rx3 (100722959), sheep P2RX3 (101104779), chicken P2RX3 (428856), cow P2RX3 (530468), dog P2RX3 (448782), naked mole-rat P2rx3 (101709018)
UniProtKB ID:
P56373, Q6DK37, Q9UQB6
Gene ID:
  • Human(5024) Summary: The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and may transduce ATP-evoked nociceptor activation. Mouse studies suggest that this receptor is important for peripheral pain responses, and also participates in pathways controlling urinary bladder volume reflexes. It is possible that the development of selective antagonists for this receptor may have a therapeutic potential in pain relief and in the treatment of disorders of urine storage. [provided by RefSeq, Jul 2008]
  • Mouse(228139) purinergic receptor P2X, ligand-gated ion channel, 3
  • Rat(81739) purinergic receptor P2X, ligand-gated ion channel, 3
  • domestic guinea pig(100722959) purinergic receptor P2X, ligand-gated ion channel, 3
  • sheep(101104779) purinergic receptor P2X, ligand-gated ion channel, 3
  • chicken(428856) purinergic receptor P2X, ligand-gated ion channel, 3
  • cow(530468) purinergic receptor P2X, ligand-gated ion channel, 3
  • dog(448782) purinergic receptor P2X, ligand-gated ion channel, 3
  • naked mole-rat(101709018) purinergic receptor P2X, ligand-gated ion channel, 3

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Antibodies

Product Number
Description
Species Reactivity
Application
P0121
Anti-Purinergic Receptor P2X3 antibody produced in rabbit, affinity isolated antibody, lyophilized powder,
Species Reactivity
rat
Application
immunohistochemistry
western blot
AB5895
Anti-P2X3 Receptor Antibody, pain, serum, Chemicon®,
Species Reactivity
human, primate, rat
Application
immunocytochemistry
immunohistochemistry
western blot
AB5896
Anti-P2X3 Receptor Antibody, pain, serum, Chemicon®,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunohistochemistry