NTRK3
neurotrophic tyrosine kinase, receptor, type 3
Synonyms:
TRKC, gp145(trkC)
Species:
Human NTRK3 (4916), Mouse Ntrk3 (18213), Rat Ntrk3 (29613), dog NTRK3 (609087), cow NTRK3 (539126), sheep NTRK3 (101121631), domestic cat NTRK3 (101085548), domestic guinea pig Ntrk3 (100731493), Horse NTRK3 (100069852), naked mole-rat Ntrk3 (101723255)
UniProtKB ID:
Gene ID:
- Human(4916) Summary: This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
- Mouse(18213) neurotrophic tyrosine kinase, receptor, type 3
- Rat(29613) neurotrophic tyrosine kinase, receptor, type 3
- dog(609087) neurotrophic tyrosine kinase, receptor, type 3
- cow(539126) neurotrophic tyrosine kinase, receptor, type 3
- sheep(101121631) neurotrophic tyrosine kinase, receptor, type 3
- domestic cat(101085548) neurotrophic tyrosine kinase, receptor, type 3
- domestic guinea pig(100731493) neurotrophic tyrosine kinase, receptor, type 3
- Horse(100069852) neurotrophic tyrosine kinase, receptor, type 3
- naked mole-rat(101723255) neurotrophic tyrosine kinase, receptor, type 3
- chicken(396081) neurotrophic tyrosine kinase, receptor, type 3
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Tyrosine Kinase Receptor C Antibody, serum, Chemicon®,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
ANTI-TRKC(N-TERMINAL) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
human
Application
immunohistochemistry
western blot
western blot
Anti-phospho-Trk C (pTyr516) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Monoclonal Anti-NTRK3 antibody produced in mouse, clone 7H6, ascites fluid,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
TRKC (507-end), active, His tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human