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Merck

NKAP

NFKB activating protein

Synonyms:
Species:
UniProtKB ID:
Gene ID:
  • Human(79576) Summary: This gene encodes a protein that is involved in the activation of the ubiquitous transcription factor NF-kappaB. This protein is associated with the the histone deacetylase HDAC3 and with the Notch corepressor complex, and it thereby acts as a transcriptional repressor of Notch target genes. It is also required for alphabeta T cell development. A related pseudogene has been identified on chromosome X, while a related and intronless retrocopy, which has an intact CDS and may be functional, is located on chromosome 6. [provided by RefSeq, May 2010]
  • Mouse(67050) NFKB activating protein
  • Rat(298342) NFKB activating protein
  • Zebrafish(336120) NFKB activating protein
  • naked mole-rat(101708216) NFKB activating protein
  • sheep(101122925) NFKB activating protein
  • dog(492098) NFKB activating protein
  • cow(540361) NFKB activating protein
  • chicken(422368) NFKB activating protein

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Small Molecule - Blocker

Product Number
Description
Species
N-p-Tosyl-L-phenylalanine chloromethyl ketone, ≥97% (TLC), powder,
Species
human

Small Molecule - Inhibitor

Product Number
Description
Species
Parthenolide, ≥98% (HPLC),
Species
human
Emodin, from Frangula bark, ≥90% (HPLC),
Species
human