MRPS18A
mitochondrial ribosomal protein S18A
Synonyms:
HumanS18b, MRP-S18-3, MRPS18-3, S18bmt
Species:
Human MRPS18A (55168), Mouse Mrps18a (68565), Rat Mrps18a (301249), dog MRPS18A (474917), domestic guinea pig Mrps18a (100731034), domestic cat MRPS18A (101089692), sheep MRPS18A (101116355), cow MRPS18A (614102), naked mole-rat Mrps18a (101707091), Zebrafish mrps18a (558080) ...More
UniProtKB ID:
Gene ID:
- Human(55168) Summary: Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S18P family. The encoded protein is one of three that has significant sequence similarity to bacterial S18 proteins. The primary sequences of the three human mitochondrial S18 proteins are no more closely related to each other than they are to the prokaryotic S18 proteins. A pseudogene corresponding to this gene is found on chromosome 3p. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jul 2010]
- Mouse(68565) mitochondrial ribosomal protein S18A
- Rat(301249) mitochondrial ribosomal protein S18A
- dog(474917) mitochondrial ribosomal protein S18A
- domestic guinea pig(100731034) mitochondrial ribosomal protein S18A
- domestic cat(101089692) mitochondrial ribosomal protein S18A
- sheep(101116355) mitochondrial ribosomal protein S18A
- cow(614102) mitochondrial ribosomal protein S18A
- naked mole-rat(101707091) mitochondrial ribosomal protein S18A
- Zebrafish(558080) mitochondrial ribosomal protein S18A
- chicken(421445) mitochondrial ribosomal protein S18A
- fruit fly(326141) mitochondrial ribosomal protein S18A
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