MAPK1
mitogen-activated protein kinase 1
Synonyms:
ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk
Species:
Human MAPK1 (5594), Mouse Mapk1 (26413), Rat Mapk1 (116590), chicken MAPK1 (373953), Zebrafish mapk1 (360144), dog MAPK1 (477575), domestic cat MAPK1 (101087614), sheep MAPK1 (101115485), cow MAPK1 (327672), naked mole-rat Mapk1 (101706099)
UniProtKB ID:
Gene ID:
- Human(5594) Summary: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene. [provided by RefSeq, Jul 2008]
- Mouse(26413) mitogen-activated protein kinase 1
- Rat(116590) mitogen activated protein kinase 1
- chicken(373953) mitogen-activated protein kinase 1
- Zebrafish(360144) mitogen-activated protein kinase 1
- dog(477575) mitogen-activated protein kinase 1
- domestic cat(101087614) mitogen-activated protein kinase 1
- sheep(101115485) mitogen-activated protein kinase 1
- cow(327672) mitogen-activated protein kinase 1
- naked mole-rat(101706099) mitogen-activated protein kinase 1
- domestic guinea pig(100715180) mitogen-activated protein kinase 1
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ELISA
Product Number
Description
Species
Cell-Based ELISA for detecting phospho-ERK1 / 2 (pThr202 / pTyr204) in cultured cell lines, 96 assays,
Species
mouse, rat, human
Cell-Based ELISA Sampler Kit for detecting phospho-ERK1/2 (pThr202/pTyr204), phospho-JNK (pThr183/pTyr185), and phospho-p38 MAPK (pThr180/pTyr182) in cultured cell lines, 192 assays,
Species
rat, human, mouse
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-MAPK1 (C-terminal) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, canine, goat, guinea pig, horse, human, mouse, rabbit, rat, zebrafish
Application
immunohistochemistry
western blot
western blot
Anti-phospho-MAP Kinase1/2 Antibody, clone 12D4, Upstate®, from mouse,
Species Reactivity
avian, canine, human, mouse, rat
Application
ELISA
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Milli-Mark® Anti-MAPK 1/2 (tERK) Antibody, Alexa Fluor 647 Conjugate, Milli-Mark®, from rabbit,
Species Reactivity
human
Application
flow cytometry
Anti-ERK2/MAPK1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
xenopus, bovine, chicken, chimpanzee, human, mouse
Application
ELISA
western blot
western blot
Anti-ERK1/ERK2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
ERK2, active, GST tagged human, recombinant, expressed in E. coli, PRECISIO® Kinase, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human