KRT80
keratin 80
Synonyms:
KB20
Species:
Human KRT80 (144501), Mouse Krt80 (74127), Rat Krt80 (315318), dog KRT80 (486534), naked mole-rat Krt80 (101706578), chicken KRT80 (431302), domestic cat KRT80 (101098552), Horse KRT80 (100061386), cow KRT80 (522400), sheep KRT80 (101113319)
UniProtKB ID:
Gene ID:
- Human(144501) Summary: Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
- Mouse(74127) keratin 80
- Rat(315318) keratin 80
- dog(486534) keratin 80
- naked mole-rat(101706578) keratin 80
- chicken(431302) keratin 80
- domestic cat(101098552) keratin 80
- Horse(100061386) keratin 80
- cow(522400) keratin 80
- sheep(101113319) keratin 80
- domestic guinea pig(100715538) keratin 80
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