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Merck

KCNMA1

potassium large conductance calcium-activated channel, subfamily M, alpha member 1

Synonyms:
BKTM, KCa1.1, MaxiK, SAKCA, SLO, SLO-ALPHA, SLO1, bA205K10.1, mSLO1
Species:
UniProtKB ID:
Gene ID:
  • Human(3778) Summary: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit, which is the product of this gene, and the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(16531) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • Rat(83731) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • domestic cat(101099080) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • cow(282573) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • sheep(100270685) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • chicken(374065) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • naked mole-rat(101726007) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • dog(403984) potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  • domestic guinea pig(100728344) potassium large conductance calcium-activated channel, subfamily M, alpha member 1

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Small Molecule - Agonist

Product Number
Description
Species
NS 1619, powder,
Species
mouse, rat
Diazoxide, ,
Species
rat, mouse, human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-KCNMA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat, sheep
Application
immunohistochemistry
western blot
Anti-KCNMA1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
xenopus, bovine, chicken, hamster, horse, human, monkey, mouse, pig, rabbit, rat, zebrafish
Application
immunohistochemistry

Small Molecule - Opener

Product Number
Description
Species
BMS 204352, ≥98% (HPLC),
Species
human
Diazoxide, ,
Species
rat, mouse, human