IDH2
isocitrate dehydrogenase 2 (NADP+), mitochondrial
Synonyms:
D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH
Species:
Human IDH2 (3418), Mouse Idh2 (269951), Rat Idh2 (361596), Thale Cress IDH2 (816218), Zebrafish idh2 (386951), dog IDH2 (479043), chicken IDH2 (431056), Domestic Rabbit IDH2 (100340796), sheep IDH2 (101102843), cow IDH2 (327669) ...More
UniProtKB ID:
Gene ID:
- Human(3418) Summary: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. Each NADP(+)-dependent isozyme is a homodimer. The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the mitochondria. It plays a role in intermediary metabolism and energy production. This protein may tightly associate or interact with the pyruvate dehydrogenase complex. [provided by RefSeq, Jul 2008]
- Mouse(269951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- Rat(361596) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- Thale Cress(816218) Isocitrate dehydrogenase [NAD] regulatory subunit 2
- Zebrafish(386951) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- dog(479043) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- chicken(431056) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- Domestic Rabbit(100340796) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- sheep(101102843) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- cow(327669) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- domestic cat(101082315) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- naked mole-rat(101708667) isocitrate dehydrogenase 2 (NADP+), mitochondrial
- domestic guinea pig(100726681) isocitrate dehydrogenase 2 (NADP+), mitochondrial
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-IDH2 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Application
western blot
Monoclonal Anti-IDH2 antibody produced in mouse, clone 5F11, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-IDH2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-IDH2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Kits
Product Number
Description
Species