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Merck

HIST2H3A

histone cluster 2, H3a

Synonyms:
H3/n, H3/o
Species:
UniProtKB ID:
Gene ID:
  • Human(333932) Summary: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy. [provided by RefSeq, Jul 2008]

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-phospho-Histone H3 (pSer28) antibody produced in rat, ~0.5 mg/mL, clone HTA28, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
bovine, hamster, human, mouse
Application
flow cytometry
immunocytochemistry

microarray

western blot
Anti-methyl-Histone H3 (Me-Lys4) antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
arabidopsis thaliana, caenorhabditis elegans, drosophila, bovine, chicken, frog, human, mouse, rat
Application
western blot
Anti-phospho-Histone H3 (pSer10) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
caenorhabditis elegans, drosophila, bovine, chicken, frog, human, mouse, rat
Application
immunofluorescence
microarray

western blot
Anti-acetyl- & phospho-Histone H3 (Ac-Lys9, pSer10) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Species Reactivity
caenorhabditis elegans, drosophila, bovine, chicken, frog, human, mouse, rat
Application
immunofluorescence
microarray

western blot
Anti-acetyl-Histone H3 (Ac-Lys9) antibody produced in rabbit, 2-2.5 mg/mL, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
caenorhabditis elegans, drosophila, bovine, chicken, frog, human, mouse, rat
Application
immunofluorescence
microarray

western blot