GRIN1
glutamate receptor, ionotropic, N-methyl D-aspartate 1
Synonyms:
GluN1, MRD8, NMDA1, NMDAR1, NR1
Species:
Human GRIN1 (2902), Mouse Grin1 (14810), Rat Grin1 (24408), naked mole-rat Grin1 (101720185), Horse GRIN1 (100059861), chicken GRIN1 (404296), sheep GRIN1 (443281), cow GRIN1 (100336579), domestic guinea pig Grin1 (100301989), dog GRIN1 (494007)
UniProtKB ID:
Gene ID:
- Human(2902) Summary: The protein encoded by this gene is a critical subunit of N-methyl-D-aspartate receptors, members of the glutamate receptor channel superfamily which are heteromeric protein complexes with multiple subunits arranged to form a ligand-gated ion channel. These subunits play a key role in the plasticity of synapses, which is believed to underlie memory and learning. Cell-specific factors are thought to control expression of different isoforms, possibly contributing to the functional diversity of the subunits. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jul 2008]
- Mouse(14810) glutamate receptor, ionotropic, NMDA1 (zeta 1)
- Rat(24408) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- naked mole-rat(101720185) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- Horse(100059861) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- chicken(404296) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- sheep(443281) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- cow(100336579) glutamate receptor, ionotropic, N-methyl D-aspartate 1
- domestic guinea pig(100301989) glutamate receptor, ionotropic, NMDA1 (zeta 1)
- dog(494007) glutamate receptor, ionotropic, N-methyl D-aspartate 1
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Custom Gene Products
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Small Molecule - Agonist
Small Molecule - Allosteric Modulator
Product Number
Description
Species
Ketamine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Species
human
Acamprosate calcium, United States Pharmacopeia (USP) Reference Standard, monograph mol wt. 400.48 (C10H20CaN2O8S2),
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-GRIN1 (pSer896) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-GRIN1 (Ab-897) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
Anti-Phospho-GRIN1-S890 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
western blot
Anti-NMDAR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-NMDAR1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Small Molecule - Blocker
Product Number
Description
Species
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
Small Molecule - Inhibitor
Product Number
Description
Species
Orphenadrine for peak identification, European Pharmacopoeia (EP) Reference Standard,
Species
human
esiRNA
Product Number
Description
Species