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Merck

GAB3

GRB2-associated binding protein 3

Synonyms:
Species:
Human GAB3 (139716), Mouse Gab3 (210710), domestic guinea pig Gab3 (100732341), naked mole-rat Gab3 (101724701), sheep GAB3 (101114497), Domestic Rabbit GAB3 (100328766), dog GAB3 (492262), Horse GAB3 (100063152), domestic cat GAB3 (101095807), chicken GAB3 (428717)
UniProtKB ID:
Q8WWW8, E9PB44
Gene ID:
  • Human(139716) Summary: This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(210710) growth factor receptor bound protein 2-associated protein 3
  • domestic guinea pig(100732341) GRB2-associated binding protein 3
  • naked mole-rat(101724701) GRB2-associated binding protein 3
  • sheep(101114497) GRB2-associated binding protein 3
  • Domestic Rabbit(100328766) GRB2-associated binding protein 3
  • dog(492262) GRB2-associated binding protein 3
  • Horse(100063152) GRB2-associated binding protein 3
  • domestic cat(101095807) GRB2-associated binding protein 3
  • chicken(428717) GRB2-associated binding protein 3
  • cow(512009) GRB2-associated binding protein 3

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