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Merck

G6PD

glucose-6-phosphate dehydrogenase

Synonyms:
G6PD1
Species:
UniProtKB ID:
Gene ID:
  • Human(2539) Summary: This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Rat(24377) glucose-6-phosphate dehydrogenase
  • dog(481088) glucose-6-phosphate dehydrogenase
  • domestic cat(100270776) glucose-6-phosphate dehydrogenase
  • Horse(100059734) glucose-6-phosphate dehydrogenase
  • cow(281179) glucose-6-phosphate dehydrogenase
  • Zebrafish(570579) glucose-6-phosphate dehydrogenase
  • Domestic Rabbit(100328765) glucose-6-phosphate dehydrogenase
  • domestic guinea pig(100722769) glucose-6-phosphate dehydrogenase
  • naked mole-rat(101712640) glucose-6-phosphate dehydrogenase
  • sheep(443211) glucose-6-phosphate dehydrogenase

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-G6PD antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-G6PD antibody produced in rabbit, ,
Species Reactivity
human, mouse
Application
western blot
Anti-G6PD antibody produced in rabbit, ,
Species Reactivity
Application
western blot
Monoclonal Anti-G6PD antibody produced in mouse, clone 5E12, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry

immunohistochemistry

western blot
Monoclonal Anti-G6PD antibody produced in mouse, clone 2H7, ascites fluid,
Species Reactivity
human
Application
ELISA
flow cytometry

immunohistochemistry

western blot

Proteins

Product Number
Description
Species
G6PD human, recombinant, expressed in E. coli, ≥95% (SDS-PAGE),
Species
human