EXOC2
exocyst complex component 2
Synonyms:
SEC5, SEC5L1, Sec5p
Species:
Human EXOC2 (55770), Mouse Exoc2 (66482), Rat Exoc2 (171455), dog EXOC2 (478696), naked mole-rat Exoc2 (101705272), domestic cat EXOC2 (101089188), sheep EXOC2 (101110975), Domestic Rabbit EXOC2 (100354138), chicken EXOC2 (420889), cow EXOC2 (513431) ...More
UniProtKB ID:
Gene ID:
- Human(55770) Summary: The protein encoded by this gene is a component of the exocyst complex, a multi-protein complex essential for the polarized targeting of exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and the functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. This interaction has been shown to mediate filopodia formation in fibroblasts. This protein has been shown to interact with the Ral subfamily of GTPases and thereby mediate exocytosis by tethering vesicles to the plasma membrane. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2012]
- Mouse(66482) exocyst complex component 2
- Rat(171455) exocyst complex component 2
- dog(478696) exocyst complex component 2
- naked mole-rat(101705272) exocyst complex component 2
- domestic cat(101089188) exocyst complex component 2
- sheep(101110975) exocyst complex component 2
- Domestic Rabbit(100354138) exocyst complex component 2
- chicken(420889) exocyst complex component 2
- cow(513431) exocyst complex component 2
- domestic guinea pig(100714267) exocyst complex component 2
- Zebrafish(100004870) exocyst complex component 2
- Horse(100049898) exocyst complex component 2
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.