EEF1E1
eukaryotic translation elongation factor 1 epsilon 1
Synonyms:
AIMP3, P18
Species:
Human EEF1E1 (9521), Mouse Eef1e1 (66143), Rat Eef1e1 (291057), sheep EEF1E1 (100135689), dog EEF1E1 (478717), domestic cat EEF1E1 (101097893), cow EEF1E1 (617105), chicken EEF1E1 (420865), domestic guinea pig Eef1e1 (100734626), naked mole-rat Eef1e1 (101706473)
UniProtKB ID:
Gene ID:
- Human(9521) Summary: This gene encodes a multifunctional protein that localizes to both the cytoplasm and nucleus. In the cytoplasm, the encoded protein is an auxiliary component of the macromolecular aminoacyl-tRNA synthase complex. However, its mouse homolog has been shown to translocate to the nucleus in response to DNA damage, and it plays a positive role in ATM/ATR-mediated p53 activation. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream MUTED (muted homolog) gene. An EEF1E1-related pseudogene has been identified on chromosome 2. [provided by RefSeq, Dec 2010]
- Mouse(66143) eukaryotic translation elongation factor 1 epsilon 1
- Rat(291057) eukaryotic translation elongation factor 1 epsilon 1
- sheep(100135689) eukaryotic translation elongation factor 1 epsilon 1
- dog(478717) eukaryotic translation elongation factor 1 epsilon 1
- domestic cat(101097893) eukaryotic translation elongation factor 1 epsilon 1
- cow(617105) eukaryotic translation elongation factor 1 epsilon 1
- chicken(420865) eukaryotic translation elongation factor 1 epsilon 1
- domestic guinea pig(100734626) eukaryotic translation elongation factor 1 epsilon 1
- naked mole-rat(101706473) eukaryotic translation elongation factor 1 epsilon 1
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