CERKL
ceramide kinase-like
Synonyms:
RP26
Species:
Human CERKL (375298), Mouse Cerkl (228094), Rat Cerkl (502640), Domestic Rabbit CERKL (100346364), sheep CERKL (101123449), domestic guinea pig Cerkl (100718349), naked mole-rat Cerkl (101708888), Zebrafish cerkl (100037318), chicken CERKL (424120), dog CERKL (488430) ...More
UniProtKB ID:
Gene ID:
- Human(375298) Summary: This gene was initially identified as a locus (RP26) associated with an autosomal recessive form of retinitis pigmentosa (arRP) disease. This gene encodes a protein with ceramide kinase-like domains, however, the protein does not phosphorylate ceramide and its target substrate is currently unknown. This protein may be a negative regulator of apoptosis in photoreceptor cells. Mutations in this gene cause a form of retinitis pigmentosa characterized by autosomal recessive cone and rod dystrophy (arCRD). Alternative splicing of this gene results in multiple transcript variants encoding different isoforms and non-coding transcripts.[provided by RefSeq, May 2010]
- Mouse(228094) ceramide kinase-like
- Rat(502640) ceramide kinase-like
- Domestic Rabbit(100346364) ceramide kinase-like
- sheep(101123449) ceramide kinase-like
- domestic guinea pig(100718349) ceramide kinase-like
- naked mole-rat(101708888) ceramide kinase-like
- Zebrafish(100037318) ceramide kinase-like
- chicken(424120) ceramide kinase-like
- dog(488430) ceramide kinase-like
- domestic cat(101096337) ceramide kinase-like
- cow(100337174) ceramide kinase-like
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