CDK8
cyclin-dependent kinase 8
Synonyms:
K35
Species:
Human CDK8 (1024), Mouse Cdk8 (264064), domestic guinea pig Cdk8 (100718250), naked mole-rat Cdk8 (101719987), sheep CDK8 (101115551), Domestic Rabbit CDK8 (100353845), domestic cat CDK8 (101086278), Zebrafish cdk8 (373868), cow CDK8 (507149), dog CDK8 (486035) ...More
UniProtKB ID:
Gene ID:
- Human(1024) Summary: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase and its regulatory subunit cyclin C are components of the RNA polymerase II holoenzyme complex, which phosphorylates the carboxy-terminal domain (CTD) of the largest subunit of RNA polymerase II. This kinase has also been shown to regulate transcription by targeting the CDK7/cyclin H subunits of the general transcription initiation factor IIH (TFIIH), thus providing a link between the 'Mediator-like' protein complexes and the basal transcription machinery. [provided by RefSeq, Jul 2008]
- Mouse(264064) cyclin-dependent kinase 8
- domestic guinea pig(100718250) cyclin-dependent kinase 8
- naked mole-rat(101719987) cyclin-dependent kinase 8
- sheep(101115551) cyclin-dependent kinase 8
- Domestic Rabbit(100353845) cyclin-dependent kinase 8
- domestic cat(101086278) cyclin-dependent kinase 8
- Zebrafish(373868) cyclin-dependent kinase 8
- cow(507149) cyclin-dependent kinase 8
- dog(486035) cyclin-dependent kinase 8
- chicken(428080) cyclin-dependent kinase 8
- Horse(100050819) cyclin-dependent kinase 8
- fruit fly(39157) Cyclin-dependent kinase 8
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Antibodies
Product Number
Description
Species Reactivity
Application
ANTI-CDK8 antibody produced in mouse, clone 5H4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-CDK8 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunoprecipitation (IP)
western blot
western blot
Anti-CDK8, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunohistochemistry
Small Molecule - Inhibitor
Product Number
Description
Species