BCL2L1
BCL2-like 1
Synonyms:
BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS
Species:
Human BCL2L1 (598), Mouse Bcl2l1 (12048), Rat Bcl2l1 (24888), Domestic Rabbit BCL2L1 (100008875), domestic guinea pig Bcl2l1 (100730495), Zebrafish bcl2l1 (114401), cow BCL2L1 (282152), domestic cat BCL2L1 (493701), chicken BCL2L1 (373954), dog BCL2L1 (403618) ...More
UniProtKB ID:
Gene ID:
- Human(598) Summary: The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator. [provided by RefSeq, Jul 2008]
- Mouse(12048) BCL2-like 1
- Rat(24888) Bcl2-like 1
- Domestic Rabbit(100008875) BCL2-like 1
- domestic guinea pig(100730495) BCL2-like 1
- Zebrafish(114401) bcl2-like 1
- cow(282152) BCL2-like 1
- domestic cat(493701) BCL2-like 1
- chicken(373954) BCL2-like 1
- dog(403618) BCL2-like 1
- sheep(443061) BCL2-like 1
- naked mole-rat(101713410) BCL2-like 1
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-BCL2L1 antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
bovine, dog, horse, human, pig, rabbit, sheep
Application
western blot
Anti-BCL2L1 antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
canine, human
Application
western blot
Anti-Bcl-X Antibody, clone 2H12, clone 2H12, Chemicon®, from mouse,
Species Reactivity
human, mouse, pig, rat
Application
flow cytometry
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
Monoclonal Anti-BCL2L1 antibody produced in mouse, clone 3E2-2A5, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
proximity ligation assay
western blot
immunofluorescence
proximity ligation assay
western blot
Anti-phospho-BCL-XL (pSer62) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Proteins
Product Number
Description
Species