ATP1A2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
Synonyms:
FHM2, MHP2
Species:
Human ATP1A2 (477), Mouse Atp1a2 (98660), Rat Atp1a2 (24212), Horse ATP1A2 (100058251), chicken ATP1A2 (396468), dog ATP1A2 (488636), domestic guinea pig Atp1a2 (100729524), naked mole-rat Atp1a2 (101721770), cow ATP1A2 (515161), sheep ATP1A2 (101118148) ...More
UniProtKB ID:
Gene ID:
- Human(477) Summary: The protein encoded by this gene belongs to the family of P-type cation transport ATPases, and to the subfamily of Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane protein responsible for establishing and maintaining the electrochemical gradients of Na and K ions across the plasma membrane. These gradients are essential for osmoregulation, for sodium-coupled transport of a variety of organic and inorganic molecules, and for electrical excitability of nerve and muscle. This enzyme is composed of two subunits, a large catalytic subunit (alpha) and a smaller glycoprotein subunit (beta). The catalytic subunit of Na+/K+ -ATPase is encoded by multiple genes. This gene encodes an alpha 2 subunit. Mutations in this gene result in familial basilar or hemiplegic migraines, and in a rare syndrome known as alternating hemiplegia of childhood. [provided by RefSeq, Oct 2008]
- Mouse(98660) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- Rat(24212) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- Horse(100058251) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- chicken(396468) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- dog(488636) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- domestic guinea pig(100729524) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- naked mole-rat(101721770) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- cow(515161) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- sheep(101118148) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- Domestic Rabbit(100008756) ATPase, Na+/K+ transporting, alpha 2 polypeptide
- domestic cat(101096785) ATPase, Na+/K+ transporting, alpha 2 polypeptide
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Na+K+ ATPase α-2 Antibody, serum, Upstate®,
Species Reactivity
rat
Application
western blot
Anti-ATP1A2 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-Sodium Pump Subunit alpha-2 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
bovine, human, mouse, porcine, rat
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Product Number
Description
Species
Digoxin, certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland,
Species
human