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Merck

ARHGAP4

Rho GTPase activating protein 4

Synonyms:
C1, RGC1, RhoGAP4, SrGAP4, p115
Species:
UniProtKB ID:
Gene ID:
  • Human(393) Summary: This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of small GTP-binding proteins belonging to the RAS superfamily. The protein encoded by the orthologous gene in rat is localized to the Golgi complex and can redistribute to microtubules. The rat protein stimulates the activity of some Rho GTPases in vitro. Genomic deletions of this gene and a neighboring gene have been found in patients with nephrogenic diabetes insipidus. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(171207) Rho GTPase activating protein 4
  • Rat(246249) Rho GTPase activating protein 4
  • domestic cat(101089250) Rho GTPase activating protein 4
  • Horse(100057993) Rho GTPase activating protein 4
  • dog(492245) Rho GTPase activating protein 4
  • sheep(101107503) Rho GTPase activating protein 4
  • cow(100124430) Rho GTPase activating protein 4
  • naked mole-rat(101725190) Rho GTPase activating protein 4
  • domestic guinea pig(100735978) Rho GTPase activating protein 4

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