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Merck

ADRA1A

adrenoceptor alpha 1A

Synonyms:
ADRA1C, ADRA1L1, ALPHA1AAR
Species:
Human ADRA1A (148), Mouse Adra1a (11549), Rat Adra1a (29412), cow ADRA1A (282134), domestic cat ADRA1A (101098375), domestic guinea pig Adra1a (100135474), dog ADRA1A (403866), sheep ADRA1A (100169940), chicken ADRA1A (428203), naked mole-rat Adra1a (101712485)
UniProtKB ID:
P35348, A8K0I3, B0ZBD1, B0ZBD2, B0ZBD4, B0ZBD5, B0ZBD6, B0ZBD8
Gene ID:
  • Human(148) Summary: Alpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq, Jul 2008]
  • Mouse(11549) adrenergic receptor, alpha 1a
  • Rat(29412) adrenoceptor alpha 1A
  • cow(282134) adrenergic, alpha-1A-, receptor
  • domestic cat(101098375) adrenoceptor alpha 1A
  • domestic guinea pig(100135474) adrenergic receptor, alpha 1a
  • dog(403866) adrenoceptor alpha 1A
  • sheep(100169940) adrenoceptor alpha 1A
  • chicken(428203) adrenoceptor alpha 1A
  • naked mole-rat(101712485) adrenoceptor alpha 1A
  • Domestic Rabbit(100009237) adrenoceptor alpha 1A

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Small Molecule - Agonist

Product Number
Description
Species
CDS000481
3-[(1R)-1-Hydroxy-2-(methylamino)ethyl]phenol, AldrichCPR,
Species
human
A0232
Alfuzosin hydrochloride, ≥98% (HPLC), solid,
Species
human
1012917
Alfuzosin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human
M6524
Methoxamine hydrochloride, ,
Species
human
BP284
Phenylephrine hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Species
human

Small Molecule - Antagonist

Product Number
Description
Species
SML1610
Dapiprazole hydrochloride, ≥98% (HPLC),
Species
human
E2031
Eliprodil, ≥98% (HPLC), powder,
Species
human, rat
B016
Benoxathian hydrochloride, solid,
Species
human
N158
Naftopidil hydrochloride hydrate, solid,
Species
human
1643452
Terazosin hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
SAB4500530
Anti-ADRA1A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
HPA076693
Anti-ADRA1A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
HTS087M
ChemiScreen Recombinant HumanMembrane Preparation

α1A Adrenergic Receptor, Human alpha1A GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Species
human