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Merck

ADH5

alcohol dehydrogenase 5 (class III), chi polypeptide

Synonyms:
ADH-3, ADHX, FALDH, FDH, GSH-FDH, GSNOR
Species:
UniProtKB ID:
Gene ID:
  • Human(128) Summary: This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. [provided by RefSeq, Oct 2008]
  • Mouse(11532) alcohol dehydrogenase 5 (class III), chi polypeptide
  • Rat(100145871) alcohol dehydrogenase 5 (class III), chi polypeptide
  • domestic guinea pig(100719427) alcohol dehydrogenase 5 (class III), chi polypeptide
  • Domestic Rabbit(100009307) alcohol dehydrogenase 5 (class III), chi polypeptide
  • sheep(101112223) alcohol dehydrogenase 5 (class III), chi polypeptide
  • cow(505515) alcohol dehydrogenase 5 (class III), chi polypeptide
  • domestic cat(101101307) alcohol dehydrogenase 5 (class III), chi polypeptide
  • dog(609781) alcohol dehydrogenase 5 (class III), chi polypeptide
  • chicken(422705) alcohol dehydrogenase 5 (class III), chi polypeptide
  • Zebrafish(116517) alcohol dehydrogenase 5
  • naked mole-rat(101717353) alcohol dehydrogenase 5 (class III), chi polypeptide

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Kits

Product Number
Description
Species
Alcohol Dehydrogenase Activity Assay Kit, sufficient for 100 colorimetric tests,
Species
rat, mouse, human