ACTN2
actinin, alpha 2
Synonyms:
CMD1AA
Species:
Human ACTN2 (88), Mouse Actn2 (11472), Rat Actn2 (291245), naked mole-rat Actn2 (101721630), domestic guinea pig Actn2 (100712846), chicken ACTN2 (396263), Zebrafish actn2 (641575), domestic cat ACTN2 (101101415), dog ACTN2 (479191), cow ACTN2 (536607) ...More
UniProtKB ID:
Gene ID:
- Human(88) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
- Mouse(11472) actinin alpha 2
- Rat(291245) actinin alpha 2
- naked mole-rat(101721630) actinin, alpha 2
- domestic guinea pig(100712846) actinin, alpha 2
- chicken(396263) actinin, alpha 2
- Zebrafish(641575) actinin, alpha 2
- domestic cat(101101415) actinin, alpha 2
- dog(479191) actinin, alpha 2
- cow(536607) actinin, alpha 2
- Horse(100033870) actinin, alpha 2
- Domestic Rabbit(100350274) actinin, alpha 2
- sheep(101116372) actinin, alpha 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Actinin α antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-alpha Actinin 2 Antibody, clone 1E11, ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse, rat
Application
immunocytochemistry
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Anti-ACTN2, affinity isolated antibody,
Species Reactivity
guinea pig, human, mouse, rabbit, rat
Application
immunohistochemistry
western blot
western blot
Anti-α-Actinin antibody produced in rabbit, whole antiserum,
Species Reactivity
chicken
Application
immunofluorescence
western blot
western blot
Monoclonal Anti-α-Actinin (Sarcomeric) antibody produced in mouse, clone EA-53, ascites fluid,
Species Reactivity
bovine, canine, chicken, feline, fish, frog, goat, hamster, human, lizard, mouse, pig, rabbit, rat, sheep, snake
Application
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Proteins
Product Number
Description
Species
α-Actinin from chicken gizzard, ~80% α-actinin basis (SDS-PAGE), ammonium sulfate suspension,
Species
mouse, chicken, rat, human